阅微基因——专注多基因联检整体ag捕鱼平台的解决方案-1000炮捕鱼机

hot search
preservation solution extraction machine dna extraction kit blood card puncher 28a 23sp y prime plus rm-y 19x fragile x smn azf deafness folic acid msi ce cardiovascular drugs cyp2c19, cyp2c9, vkorc1

clinical research

msi detection kit

msi detection kit

features

■ accurate: 
containing all nci recommended mononucleotide locus, highly sensitive and specific.
■ convenient:
single-tube amplification, applicable for automatic and batched detection.
■ fast: 
get results within 6 hours.

loci detected

interpretation standard

workflow

instrument

gene analyzer (abi prism 310, 3100 genetic analyzer, or abi 3130 series, 3500 series, 3730 series genetic analyzer)

application

nccn clinical practice guidelines in oncology: colon cancer(2019.v2)


universal mmr or msi testing is recommended in all patients with a personal colon/rectal cancer to identify individuals with lynch syndrome.

stage ii msi-h colon/rectal cancer patients may have a good prognosis and do not benefit from 5-fu adjuvant therapy. 

for patients with deficient mismatch repair (dmmr) or microsatellite instability-high (msi-h) tumors, nivolumab or pembrolizumab added as treatment options in subsequent therapy for patients appropriate for intensive therapy. 


※reference:
nccn clinical practice guidelines in oncology: colon cancer(2019.v21)
https://www.fda.gov/newsevents/newsroom/pressannouncements/ucm560167.htm
※for research use only